Product Information

HOWARU® HN019™

  • 81 preclinical study publications​
  • ~68 clinical trial publications​

Health Benefits:

Early Life Development

Digestive Health

Immune Health

Oral Health

HOWARU® Bifidobacterium lactis HN019™ has been consumed in dairy foods for decades and is well-studied for its probiotic properties in more than 180 scientific publications. It has been demonstrated to tolerate acidic conditions and shown to survive passage through the human intestine.¹⁻³ ​

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HOWARU® GI Complete

HOWARU® GI Complete is a unique probiotic blend for gastro-intestinal wellbeing.

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HOWARU® Kids Digestive Health

HOWARU® Kids Digestive Health is a documented probiotic to support digestive health in children.​

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HOWARU® Protect 55+

HOWARU® Protect 55+ supports immune enhancements in aging adults.

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HOWARU® Smile

HOWARU® Smile supports a healthy smile.

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HOWARU® Transit

HOWARU® Transit has been studied to effectively shorten colonic transit time, support healthy digestion, and ease digestive discomfort.

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HN019™ CLINICAL STUDIES & PUBLICATIONS

Mechanistic data suggests HN019™ may influence colonic motility, and multiple clinical trials with HN019™ alone or in combination with prebiotics or other probiotic strains have resulted in increased gut transit in persons with less frequent bowel movements positioned for adults as HOWARU® Transit and for kids as HOWARU® Kids Digestive Health.⁴⁻⁶

HOWARU® Protect 55+ has also been shown to modulate immune function, particularly enhancing cellular immune activity in aging persons.⁷ It also offers oral health benefits as HOWARU® Smile offering a natural, alternative way to support healthy gum tissue and promote an overall healthy smile.

HOWARU® HN019™

Health Benefit Area

Supporting Daily Dose

Study Reference

Digestive Health

2B and 17B CFU HN019™

Waller PA, et al. Scand J Gastroenterol. 2011;46(9):1057-1064.

Digestive Health

5B CFU HN019™

Hemalatha R, et al. EJNF. 2014; 4(4):325-341.

Immune Health

5B CFU minimum HN019™

Miller LE, et al. Nutrients. 2017; 9(3):191.

Oral Health

2B CFU HN019™

Invernici M, et al. J Clinical Periodontology. 2018;45(10):1198-1210.

de Almeida Silva Levi YL, et al. Clin Oral Investig. 2022;27(1):387-398.

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References:1. Gopal PK et al.; Nutrition Research. 2003; 2. Prasad J et al.; Intl Dairy J. 2013; 3. Wickens K et al.; J Allergy Clinical Immunology. 2008; 4. Dalziel Je et al.; Frontiers in Neuroscience. 2017; 5. Ibarra A et al.; Gut Microbes. 2017; 6. Waller PA et al.; Scandinavian J Gastroenterology. 2011; 7. Miller LE et al.; Nutrients. 2017.

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We’d love to talk to you about how our microbiome and bioscience expertise can help you develop, manufacture and deliver solutions that enable people at all life stages to live healthier and happier lives.

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