Study Aim
The effect of orally consumed phosphatidylserine (PS) from soy on skin moisture content and wrinkles.
Product Information
Sharp-PS® for Beauty
Health Benefits:
Beauty
Phosphatidylserine (PS) is backed by more than 50 clinical studies, for multiple indication, as well as by a significant volume of pre-clinical evidence demonstrating the safety profile and likely mechanism of action.
ADVANTAGES
Advantages of PS for Beauty
• Supports skin health
• Wrinkle reduction
• Improves skin moisture levels
A NATURAL NUTRIENT FOR BODY AND MIND
PS is a thoroughly researched ingredient that demonstrates benefits supporting both body and brain. Derived from soy and sunflower, Sharp-PS® has been clinically-tested to improve cognitive performance in students¹, attention and behavior in children,² in addition to helping to minimize feelings of stress for those who excite easily,³ while supporting overall skin health.⁴ We also have a sunflower derived version called Sharp-PS® Green.
PHOSPHATIDYLSERINE (PS) SKIN CLINICAL TRIAL
Learn more about the phosphatidylserine (PS) clinical trial and endpoints:
Study Design
Double-blinded, placebo-controlled clinical trial.
Study Method
70 healthy Korean female volunteers, 40 -60 years, with wrinkles, divided into two groups:
• PS (300mg/day, split between 2 capsules)
• Placebo
Assessments conducted at baseline, 6 and 12 weeks.
Endpoints
• Skin wrinkles assessed by dermatologist’s visual evaluation and 3D skin surface replica analysis (Skin-Visiometer SV 600).
• Skin moisture assessed by Corneometer® CM825.
PHOSPHATIDYLSERINE (PS) CLINICAL TRIAL RESULTS
Wrinkles and Moisture Improved at 12 Weeks
Compared to placebo, 12 weeks PS supplementation resulted in:
1. Reduced wrinkles:
- Reduced photodamage scores, P=0.001
- Reduced 3D skin roughness values, P<0.055
2. Improved skin moisture values, P<0.055
Changes in the global photodamage score in placebo and PS-supplemented group in clinical study
Week | Placebo | D | PS-supplemented | D | P-value |
|---|---|---|---|---|---|
0 | 3.47 ± 1.02 | 3.290 ± 1.04 | |||
6 | 3.44 ± 0.95 | -0.03 ± 0.18 | 3.19 ± 1.14 | -0.10 ± 0.30 | 0.083 |
12 | 3.44 ± 0.98 | -0.03 ± 0.18 | 2.97 ± 1.14 | -0.32 ± 0.48 | 0.001 |
References: 1. Tang et al., Chongqing Medicine., 2011; 2. Hirayama et al., J Hum Nutr Diet., 2014; 3. Benton et al., Nutr. Neurosci., 2001; 4. Choi et al. J Korean Soc Appl Biol Chem., 201; 5. Choi et al. 2013
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