Product Information
HOWARU® Calm
HOWARU® Lacticaseibacillus paracasei Lpc-37® has been cited in more than 65 scientific publications, including more than 21 clinical trials. It has a long history of safe use, is well suited for intestinal survival, and has strong adhesion to intestinal cell lines and pathogen inhibition.¹˒²
- Tailor-made products for the consumer you are targeting
- Demonstrated safe, well tolerated, clinically documented³˒⁴ probiotics
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Helping consumers support their mood health by:
• Promoting mental wellbeing and a relaxed state of mind
• Balancing and regulating feelings of stress
• Managing the mental response to stress
The prevalence of stress and its effects continue to grow and negatively impact health and productivity. A clinical trial of HOWARU® Calm (HOWARU® Lpc-37®) demonstrated benefits in helping manage the psychological response to stress, promoting mental well-being, and helping balance and regulate perceived feelings of stress.
References: 1. Ouwehand AC, DongLian C, Weijian X, et al. Probiotics reduce symptoms of antibiotic use in a hospital setting: a randomized dose response study. Vaccine. 2014;32:458-463; 2. Patterson E, Griffin SM, Ibarra A, Ellsiepen E, Hellhammer J. Lacticaseibacillus paracasei Lpc-37® improves psychological and physiological markers of stress and anxiety in healthy adults: a randomized, double-blind, placebo-controlled and parallel clinical trial (the Sisu study). Neurobiol Stress. 2020;13:100277. doi: 10.1016/j.ynstr.2020.100277; 3. Ding WK, Shah NP. Acid, bile and heat tolerance of free and microencapsulated probiotic bacteria. J Food Sci. 2007;72:M446-450; 4. Gibson GR, McCartney AL, Rastall RA. Prebiotics and resistance to gastrointestinal infections. Br J Nutr. 2005;93(Suppl. 1):S31-34.
We’d love to talk to you about how our microbiome and bioscience expertise can help you develop, manufacture and deliver solutions that enable people at all life stages to live healthier and happier lives.