Product Information

HOWARU® Lpc-37®

  • 126 scientific publications
  • 50+ clinical trials

Health Benefits:

Brain Health

Digestive Health

HOWARU® Lacticaseibacillus paracasei​ Lpc-37® can be paired with other strains like NCFM®, Bi-07®, and Bl-04® in our HOWARU® Restore blend. Together, they support gut health, lessen the days of gut disruption and support overall digestive health.¹ Beyond digestion, Lpc-37® has been investigated for its impact on managing the psychological response to stress as HOWARU® Calm.² It’s not just about the gut—it’s about holistic wellbeing.

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HOWARU® Calm

HOWARU® Calm is a probiotic for the gut-brain axis that reduces perceived stress.

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HOWARU® GI Complete

HOWARU® GI Complete is a unique probiotic blend for gastro-intestinal wellbeing.

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HOWARU® Restore

HOWARU® Restore promotes good digestive health during episodes of gut stress.

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Lpc-37® CLINICAL STUDIES & PUBLICATIONS

Lpc-37® has been cited in more than 65 scientific publications, including more than 47 clinical trials. It has a long history of safe use, is well-suited for intestinal survival, and has strong adhesion to intestinal cell lines and pathogen inhibition.³ ⁴

HOWARU® Lpc-37®

Health Benefit Area

Supporting Daily Dose

Study Reference

Brain Health

17B CFU Lpc-37®

Patterson E, et al. Neurobiol Stress. 2020;13:100277.

Digestive Health

2B CFU Lpc-37®

Hemalatha R, et al. EJNF. 2014; 4(4):325-341.

Digestive Health

17B (equal parts) CFU Bl-04®, NCFM®, Bi-07®, Lpc-37®

Ouwehand AC, et al. Vaccine. 2014;32(4):458-463.

Digestive Health

2.5B CFU NCFM®, 2.5B CFU Lpc-37®, 2.5B CFU Bl-04®, 2.5B CFU Bi-07®, 2B CFU HN019

Harris L, et al. J Clin Gastroenterol. 2022; 56(5):444-451

Digestive Health

10B CFU Total Bi-07®, Bl-04®, NCFM®, Lpc-37®

van Zanten G, et al. Microorganisms. 2024; 12(4),796.

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References: 1. Ouwehand AC, et al.;Vaccine. 2014​; 2. Patterson E, et al;.Neurobiol Stress. 2020​; 3. Ding WK, et al;,J Food Sci. 2007​; 4. Gibson GR, et al,; Br J Nutr. 2005.

How can we help?​

We’d love to talk to you about how our microbiome and bioscience expertise can help you develop, manufacture and deliver solutions that enable people at all life stages to live healthier and happier lives.

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